Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Non-financial conflicts of interest

Some of the most consequential conflicts in oncology and medicine overall are not financial; these remain poorly defined and weakly regulated. Here we offer a policy-relevant definition and examine how reputation, ambition, ideology and institutional loyalty can shape research, guidelines, policy and hiring decisions. We argue for structural safeguards to preserve trust in medicine.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Visible and hidden conflicts of interest in medicine.

References

  1. Institute of Medicine (US) Committee on Conflict of Interest in Medical Research, Education, and Practice. Institutional conflicts of interest. In Conflict of Interest in Medical Research, Education, and Practice (eds Lo, B. & Field, M. J.) https://www.ncbi.nlm.nih.gov/books/NBK22934/ (US National Academies Press, 2009).

  2. Resnik, D. B. Disclosing and managing non-financial conflicts of interest in scientific publications. Res. Ethics Rev. 19, 121–138 (2023).

    Article  Google Scholar 

  3. Flaherty, D. K. Ghost- and guest-authored pharmaceutical industry-sponsored studies: abuse of academic integrity, the peer review system, and public trust. Ann. Pharmacother. 47, 1081–1083 (2013).

    Article  PubMed  Google Scholar 

  4. Dyer, O. Harvard’s Dana-Farber Cancer Institute to retract multiple papers after blogger alleges data fabrication. BMJ 384, q249 (2024).

    Article  PubMed  Google Scholar 

  5. Miles, J. Federal government orders review of treatment guidelines for trans and gender diverse children. Australian Broadcasting Corporation https://www.abc.net.au/news/2025-01-31/federal-review-treatment-guidelines-trans-gender-diverse-kids/104882406 (31 January 2025).

  6. Shubeck, S. P., Newman, E. A., Vitous, C. A., Antunez, A. G. & Dossett, L. A. Hiring practices of US academic surgery departments—challenges and opportunities for more inclusive hiring. J. Surg. Res. 254, 23–30 (2020).

    Article  PubMed  Google Scholar 

  7. Piller, C. Is FDA’s revolving door open too wide? Science 361, 21 (2018).

    Article  CAS  PubMed  Google Scholar 

  8. Sawalha, L. et al. Analysis of repeated roles in editorial boards at oncology focused journals. J. Cancer Policy 35, 100380 (2023).

    Article  PubMed  Google Scholar 

  9. Bartlett, T. ‘You could throw out the results of all these papers’. The Atlantic https://www.theatlantic.com/health/archive/2025/07/david-geier-vaccine-safety-shoddy-research/683630/ (2025).

  10. McCarthy, M. Former Duke University oncologist is guilty of research misconduct, US officials find. BMJ 351, h6058 (2015).

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We thank D. Resnik from NIEHS, NIH, USA, for his review of an earlier version of this manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Saroj Niraula.

Ethics declarations

Competing interests

The authors declare no financial competing interests. Both authors have long engaged academically with conflicts of interest in medicine, which might be relevant to the perspectives expressed.

Additional information

Related links

The International Committee of Medical Journal Editors: https://www.icmje.org/

The World Health Organization: https://www.who.int/

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Niraula, S., Tannock, I.F. Non-financial conflicts of interest. Nat Rev Clin Oncol (2025). https://doi.org/10.1038/s41571-025-01073-3

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41571-025-01073-3

Search

Quick links

Nature Briefing Careers

Sign up for the Nature Briefing: Careers newsletter — what matters in careers research, free to your inbox weekly.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing: Careers