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Melatonin prevents diabetes mellitus-induced bone loss

Nature Reviews Endocrinology volume 17, page 707 (2021)Cite this article

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Type 1 diabetes mellitus (T1DM) is known to be associated with osteoporosis in many patients. This osteoporosis is in part due to increased cellular senescence, which causes reduced bone turnover. Melatonin has anti-senescent effects. However, its efficacy in the context of T1DM-induced osteoporosis is currently unclear. A new paper in Osteoporosis International investigates whether melatonin can reduce senescence and prevent bone loss in the context of hyperglycaemia and T1DM.

bone loss was alleviated by melatonin treatment

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  1. Nature Reviews Endocrinology http://www.nature.com/nrendo/

    Olivia Tysoe

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  1. Olivia Tysoe
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Correspondence to Olivia Tysoe.

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Tysoe, O. Melatonin prevents diabetes mellitus-induced bone loss. Nat Rev Endocrinol 17, 707 (2021). https://doi.org/10.1038/s41574-021-00581-3

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