Addressing ethical, legal and social implications (ELSI) in genomics requires early integration of specialized teams to enhance community engagement, address disparities and promote health equity. Lessons learnt from the human Developmental Genotype-Tissue Expression (dGTEx) project show how implementing a collaborative framework can support genomic discovery.
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Acknowledgements
The dGTEx project would not be possible without the generosity of donor families who have provided such precious gifts to support this important work. The authors are grateful to them and their child’s legacy. This work would also not be possible without our organ procurement organization partners, CAB and PISAC members, whose ongoing commitment to this project has already created an immeasurable impact.
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Hernandez, R.G., Guambaña, S., VonDran, M.W. et al. Integrating ELSI study teams in paediatric genomic research efforts. Nat Rev Genet 26, 223–224 (2025). https://doi.org/10.1038/s41576-025-00818-1
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DOI: https://doi.org/10.1038/s41576-025-00818-1
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