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Integrating the genome and exposome for precision health in Kuwait

Nature Reviews Genetics volume 26, pages 735–736 (2025)Cite this article

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Extreme environmental conditions create stressors that can interact with genetic predispositions to influence health outcomes. With some of the highest global rates of chronic complex diseases and a high prevalence of consanguinity, Kuwait offers an unprecedented opportunity to study gene–environment interactions at scale.

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Authors and Affiliations

  1. Dasman Diabetes Institute (DDI), Dasman, Kuwait

    Hamad Ali, Barrak Alahmad, Faisal H. Al-Refaei & Fahd Al-Mulla

  2. Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Health Sciences Center (HSC), Kuwait University, Jabriya, Kuwait

    Hamad Ali

  3. Environmental Health Department, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA

    Barrak Alahmad

  4. Dubai Health Genomic Medicine Center, Dubai Health, Dubai, United Arab Emirates

    Ahmad Abou Tayoun

  5. Qatar Foundation, Doha, Qatar

    Hilal A. Lashuel

  6. Weil Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, Qatar

    Hilal A. Lashuel

  7. Department of Neurology, Weil Cornell Medicine, New York, NY, USA

    Hilal A. Lashuel

  8. Authority For Medical Responsibility, Kuwait City, Kuwait

    Salman Al Sabah

Authors
  1. Hamad Ali
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  2. Barrak Alahmad
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  3. Faisal H. Al-Refaei
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  4. Ahmad Abou Tayoun
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  5. Hilal A. Lashuel
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  6. Salman Al Sabah
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  7. Fahd Al-Mulla
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Corresponding author

Correspondence to Hamad Ali.

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The authors declare no competing interests.

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Workshop: https://www.nationalacademies.org/our-work/precision-medicine-promoting-knowledge-exchange-and-collaboration-between-kuwait-and-the-united-states-workshop-series

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Ali, H., Alahmad, B., Al-Refaei, F.H. et al. Integrating the genome and exposome for precision health in Kuwait. Nat Rev Genet 26, 735–736 (2025). https://doi.org/10.1038/s41576-025-00883-6

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