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ALZHEIMER DISEASE

Could HIV drugs treat AD?

Nature Reviews Neurology volume 15, page 4 (2019)Cite this article

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Somatic gene recombination of a gene that is central to Alzheimer disease (AD) occurs in the brain, according to a new study published in Nature. The finding could change our understanding of AD pathogenesis and suggests that existing HIV therapies could be useful in the treatment of AD.

Earlier in his career, Jerold Chun, senior author of the new study, demonstrated that part of the immunological recombinase is expressed in the brain. This finding initiated a search for a gene that undergoes recombination in the brain.

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  1. Nature Reviews Neurology http://www.nature.com/nrneurol/

    Ian Fyfe

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  1. Ian Fyfe
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Correspondence to Ian Fyfe.

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Fyfe, I. Could HIV drugs treat AD?. Nat Rev Neurol 15, 4 (2019). https://doi.org/10.1038/s41582-018-0118-4

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