Extended Data Fig. 7: MLH1 hypermethylation in P1.
From: Intra-tumour diversification in colorectal cancer at the single-cell level
a–c, Methylation pattern of the MLH1 gene for tumour and normal clones for three individuals, showing hypermethylation in proximity to the transcription start site (TSS) for P1 tumour clones compared to normal clones. d, Expression of MLH1 in all clones; MLH1 transcript could not be detected in tumour clones from P1.
