Extended Data Fig. 1: Origin of clonal organoids analysed in this study.
From: Intra-tumour diversification in colorectal cancer at the single-cell level
Specimens were derived from the ascending colon of a 66-year-old woman (a–f), sigmoid rectum of a 65-year-old woman (g–n) and ascending transverse colon of a 56-year-old man (o–t), respectively. From each tumour, 4–6 segments were resected (sized 5 × 5 × 3–5 mm. All sections except T3 from P2 resulted in viable clonal organoids. b–f, h–n, p–t, Haematoxylin and eosin staining and Ki67 immunohistochemistry show cell morphology for individual tumour sections. Scale bars: 200 µm.
