Extended Data Fig. 4: Aspm knockout mice do not demonstrate displaced progenitors in the intermediate zone.
From: Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size

a, b, Unlike Aspm−/− ferrets, Aspm−/− mice do not have displaced NPCs in the intermediate zone. However, they show a variable increase in the number of intermediate progenitors (PAX6−Ki-67+ cells in a and TBR2+ cells in b), which is enhanced by heterozygous, compound mutation in Wdr62, a microcephaly gene causing more severe microcephaly9. The experiments were repeated independently three times with similar results. Scale bars, 100 μm.