Extended Data Fig. 6: Motif analysis of ADNP-bound loci.
From: Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes
a, ADNP DNA-binding motifs predicted by HOMER. Frequency of occurrence and P values for motif enrichment compared to genomic background are indicated. n = 3 independent cell lines. b, Analysis of co-occurrence of the top-ten scoring ADNP DNA motifs. The bar graph shows the frequency of peaks containing the top-scoring ADNP motif and up to nine additional motifs as indicated on the x axis. Note that most peaks besides the GCCCCCTGGAG motif also contain more than five other sequence motifs out of the top-ten list.
