Extended Data Table 3 Cell counts of viable aortic cells determined using FACS analysis

From: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

  1. Cell counts of viable aortic cells isolated from aortas of chow-fed and HCD-fed Ldlr−/− mice and HCD-fed Ldlr−/−E06-scFv mice. Values are mean ± s.d. of total viable cells evaluated by flow cytometry per aorta as described in the Methods. Number of aorta for each group: n = 5 HCD-fed Ldlr−/−E06-scFv mice; n = 6 chow-fed Ldlr−/− mice and n = 6 HCD-fed Ldlr−/− mice.
  2. *Note that one aorta from one HCD-fed Ldlr−/− mouse had extensive atherosclerosis and had 27,846 viable cells counted. The next highest value in this group was 9,342. By comparison, the highest in the Chow-fed Ldlr−/− group was 2,909 and in the HCD-Ldlr−/−E06-scFv group was 5,692. Aortic cells were evaluated by flow cytometry as described in the Methods. Data for phenotypes of monocyte/macrophages are shown in Fig. 3.
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