Extended Data Fig. 2: Unprotected haematopoietic cells accumulate DNA damage after UV irradiation.
From: Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche
a, Sorted cells that were positive for Tg(runx:mCherry) after anti-CPD immunostaining. Scale bars, 10 μm. b, Dot plot representation of data in Fig. 2b (quantification of immunostaining intensity per cell). Data are mean ± s.d.; for statistics and P values please refer to Fig. 2b. c, Magnification of the thymus (dashed red outline) after anti-CPD immunostaining (counterstaining with haemalum) after UVB irradiation at 5 dpf in pigmented and non-pigmented larvae. Arrows from above indicate melanocytes; arrows from below indicate examples of nuclei with DNA damage.
