Extended Data Fig. 5: HSPCs relocated into the bone marrow before the transition to a terrestrial environment.
From: Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche
a, Top, a developmental time line of D. tinctorius. Tadpoles were staged according to Gosner34. Animals (from left to right) represent Gosner stage 25, 30, 41 and 42, as well as a froglet five days after losing its tail. Stage-specific histology analyses are shown in panels b–f as indicated. Bottom, the habitat of D. tinctorius at the different developmental stages. b–f, Haematopoietic niches analysed by haematoxylin and eosin staining. Scale bars, 100 μm (b–f) and 1 cm (a).
