Extended Data Fig. 8: CT scan evaluation of the tumours and adipose tissue before and after BYL719 introduction.
From: Targeted therapy in patients with PIK3CA-related overgrowth syndrome
a, Body weight evolution of PIK3CAWT and PIK3CACAGG-CreER mice treated with vehicle or BYL719 (n = 3 mice per group). b, CT scan evaluation and quantification of the fat tissue content in PIK3CAWT and PIK3CACAGG-CreER mice treated with vehicle or BYL719. Subcutaneous and visceral fat content were measured before treatment and 7 and 14 days after onset of treatment with vehicle or BYL719 (n = 3 mice per group). c, CT scan evaluation and quantification of tumour volume in PIK3CACAGG-CreER mice before and after two weeks of BYL719 treatment (arrows) (n = 3 mice per group). All data are shown as mean ± s.e.m.
