Extended Data Fig. 2: CK-689 does not significantly alter movement of foci.
From: Nuclear ARP2/3 drives DNA break clustering for homology-directed repair
a, Summary of DSB movement analyses as related to Figs. 3, 6, and Extended Data Fig. 5. b, MSD of RAD52–mCherry foci and RPA–pEGFP–NLS foci treated with DMSO, CK-689 and CK-666. Data shown as mean and weighted s.e.m.; RAD52: CK-689 n = 3,262 foci from 13 nuclei, CK-666 n = 2,143 foci from 12 nuclei, DMSO n = 3,292 foci from 12 nuclei; RPA32: CK-689 n = 790 foci from 13 nuclei, CK-666 n = 823 foci from 12 nuclei, DMSO n = 1,031 foci from 10 nuclei. MSD of RAD52 DMSO also shown in Fig. 6i. MSD of RAD52 CK-689 and CK-666 also shown in Fig. 3g. MSD of RPA CK-689 and CK-666 also shown in Fig. 3k.
