Extended Data Fig. 5: Cell surface expression of α6 integrin is variable across a panel of ALL cell lines and primary human ALL cells in vitro and in vivo.
From: Leukaemia hijacks a neural mechanism to invade the central nervous system
a, Flow cytometry analysis of the percentage of α6 integrin+ populations in ALL cell lines and primary ALL cells. Data are mean ± s.e.m.; n = 3 independent experiments per cell line. b, Representative flow cytometry histograms of α6 integrin expression in ALL cell lines and primary ALL cells. n = 3 independent experiments. c, Representative α6 integrin immunohistochemistry of femoral bone marrow from mice engrafted with low α6 integrin-expressing versus high α6 integrin-expressing ALL cells. α6 integrin low primary human ALL: n = 6 mice; REH: n = 6 mice; SUP-B15: n = 3 mice; RCH-ACV: n = 6 mice; Nalm-6: n = 10 mice.
