Extended Data Fig. 4: Microarray analysis of focal adhesion and motility pathway genes in blasts from vehicle- versus GS-649443-treated mice and validation of key candidates.
From: Leukaemia hijacks a neural mechanism to invade the central nervous system
a, b, Differentially expressed focal adhesion and motility pathway genes identified by microarray analysis of blasts from vehicle- versus GS-649443-treated mice. n = 6 mice per treatment group. c, Microarray negative control validation. Representative flow cytometry analysis of Nalm-6 expression of CXCR4, CXCR3, CD44 and CD24 following treatment with vehicle or GS-649443. n = 3 independent experiments. d, ALL α6 integrin expression in vivo by flow cytometry. Data are mean ± s.e.m.; n = 4 mice.
