Extended Data Fig. 2: s-CANC and s-CASP1 VLPs.

a–c, Representative negative-stain electron microscopy images of s-CANC (a), s-CASP1 (b) and s-CA (c) proteins assembled in the absence of GT25 and in the presence of the indicated IP6 concentrations. Scale bars, 200 nm. d, Diameters of immature VLPs; mean diameter above plot; n below plot. Centre lines show medians; box limits indicate 25th and 75th percentiles as determined by R software; whiskers extend to minimum and maximum values.