Extended Data Fig. 8: ser-4 is necessary for PHB > AVA and PHA > AVG synaptic pruning and acts downstream of the ADF serotonin signal.
From: Past experience shapes sexually dimorphic neuronal wiring through monoaminergic signalling
a, Starvation does not enhance the male synaptic pruning defect in ser-4 mutants, and the ser-4 mutant phenotype cannot be rescued by exogenous serotonin. Each dot represents one animal (n = number of animals, shown in each column), blue bar represents median, black box represents quartiles, vertical black bars represent range. P values calculated by two-sided Wilcoxon rank-sum test (a, b). b, Expression of a tph-1 transcriptional fosmid in NSM and ADF does not significantly differ between wild-type and ser-4 mutant L1 animals. Each dot represents the expression level of one animal, n = number of animals, shown in each column. Magenta bar indicates median, black box represents quartiles.
