Extended Data Fig. 2: Activation of β1 integrin, VEGFR3 and total β1 integrin expression in ECs of E11.5 livers.
From: Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival
a, a′, b, b′, Transversal sections through livers with quantified areas of activated endothelial β1 integrin (for quantification, see Fig. 1m). c, c′, d, d′, Transversal sections with VEGFR3 tyrosine phosphorylation indicated by PLA (red dots and white arrowheads; for quantification, see Fig. 1n). e, e′, f, f′, g, Transversal sections with total β1 integrin (e, f) and quantified area of total endothelial β1 integrin (e′, f′) in liver centre versus liver periphery (g, n = 4 livers, P = 0.316 (−44.98; 99.49)). Scale bars, 25 μm. Two-tailed paired Student’s t-tests, 95% confidence interval (lower confidence limit; upper confidence limit).
