Extended Data Table 4 Polygenic score analyses comparing patients from the DDD with an exome diagnosis (n = 1,127) against undiagnosed patients (n = 2,479)

From: Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

  1. P values are uncorrected, two-sided and from z-score distribution.
  2. aLogistic regression of diagnosed and undiagnosed status on polygenic score, using ten ancestry principal components as covariates.
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