Extended Data Table 5 Polygenic score analyses in patients from the DDD for measured traits

From: Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

  1. P values are uncorrected, two-sided and from t-distribution (linear) and z-score distribution (logistic). aLinear or logistic regression on polygenic score. using ten ancestry principal components as covariates.
  2. bSevere cases were labelled as 1 in the logistic regression.
  3. cNagelkerke R2.