Extended Data Table 1 Defective N-linked protein glycosylation in CD4+ T cells exposed to ascites

From: IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

  1. CD4+ T cells were activated with anti-CD3 and anti-CD28 beads in the presence or absence of ascites for 16 h. Cells were lysed and the enriched glycoprotein fractions were analysed for N-linked glycosylation events by LC–MS/MS. Representative glycoproteins recovered from both control and ascites-exposed CD4+ T cells. The table shows each site for N-linked glycosylation on the identified protein, the glycan type on that site and the number of glycosylation events identified in each glycoform. The per cent decrease in glycosylation upon ascites exposure was calculated using the following equation: per cent decrease in glycosylation = 100 – (number of total glycosylation eventsascites divided by the number of total glycosylation eventscontrol) × 100.
  2. *Altered event.
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