Extended Data Fig. 7: IFNγ ELISPOT responses following ART discontinuation and trends for viral rebound.
From: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys
a, Gag-, Env-, and Pol-specific IFNγ ELISPOT responses in PBMCs are shown at day 140 following ART discontinuation (n = 11 monkeys per group). SFCs per million PBMCs are shown. Monkeys in each group that demonstrated viral rebound versus no rebound are shown separately. Red horizontal bars indicate median values. The dotted line represents the assay limit of quantitation (55 SFCs per million PBMCs). b, Trends for viral rebound are shown in the GS-9620 and PGT121 groups in relation to pre-ART week 1 viral loads, supplementing the data shown in Fig. 5c. Red horizontal bars indicate median values.
