Extended Data Fig. 4: Drug response in de novo versus transformed AML cases.
From: Functional genomic landscape of acute myeloid leukaemia
The average inhibitor response AUCs for all cases that were de novo (n = 288) versus all cases that transformed from a background of myelodysplastic syndromes (n = 111) were compared for every inhibitor that had at least three cases with evaluable data in each group. The middle point represents the average difference in AUC between the two groups with the bars representing the 95% confidence interval. For the sample size and statistical results of each drug–sample group correlation, see Supplementary Table 20.
