Extended Data Fig. 4: Tension–strain relations in MDCK–CAAX and Caco2 cells.
From: Active superelasticity in three-dimensional epithelia of controlled shape
a, Relation between surface tension and areal strain for MDCK–CAAX cells. Data include measurements at different time points from n = 9 domes. The tension–strain relation is qualitatively similar to the one obtained for MDCK–LifeAct cells (Fig. 3e), with small quantitative differences. The solid line and shaded area indicate the mean ± s.d. obtained by binning the data (n = 14 points per bin). b, Image of a representative Caco2-cell dome labelled with BODIPY FL C16 dye (n = 3 micropatterned substrates). Confocal x–y, x–z and y–z sections are shown. Scale bar, 50 μm. c, Relation between surface tension and areal strain for Caco2 cells. Data include measurements at different time points from n = 6 domes. Caco2 cells show a tensional plateau throughout the probed strain range. The solid line and shaded area indicate the mean ± s.d. obtained by binning the data (n = 10 points per bin).
