Extended Data Fig. 1: Co-crystal structures and superimposition of compounds 1 and 2.
From: Design of amidobenzimidazole STING receptor agonists with systemic activity
a, Superposition of compound 1 (PDB code: 6DXG) and the diABZI compound 2 (PDB code: 6DXL) bound to human STING (aa 149–379). b, Intermolecular contacts in the complex of compounds 1 and 2 bound to human STING (aa 149–379). Magenta, compound 1; green, compound 2. Corresponding subunits of STING shown in same colour for compounds 1 and 2. c, Electron density (1.0σ) of compound 1. d, Electron density of (0.5σ) of compound 2.
