Extended Data Fig. 3: The developing right inner ear of the hagfish.
From: Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals
a, A 3D model of the stage-51–53 embryo, reconstructed from histological serial sections (n = 1 biological replication), shown in a dorsal view, with anterior to the left and lateral to the top. b–f, Sagittal histological sections of the inner ear at levels indicated by dashed lines in a. There can be variations in inner ear development among hagfish species. For example, the central hole of the Myxine glutinosa inner ear is penetrated by cartilage4, whereas the equivalent space is filled by mesenchyme in E. burgeri (c). Image shown with anterior to the left, and dorsal to the top. oc, otic capsule. See Fig. 2 for other abbreviations. Scale bar, 100 μm.
