Extended Data Fig. 1: Study design.
From: Age-related remodelling of oesophageal epithelia by mutated cancer drivers
a–c, Summary of the subjects, samples, methods of sample collection, lifestyle ESCC risks, and histology, as well as sequencing platforms used for analysis of solitary samples (a), single-cell-derived colonies (b) and densely collected samples (c). *In one case (UPN53), only cancer and dysplasia samples were collected. §, UPN36, UPN37 and UPN39; ¶, UPN49; ‡, UPN88; #, UPN56 and UPN61; Φ, UPN58; ††, UPN55, UPN59, UPN60 and UPN65. Samples from these individuals were analysed in indicated multiple experiments (see a, b and c). †Out of 53 PNE samples, 11 were analysed in both solitary and high-density sampling (see a and c).
