Extended Data Fig. 4: gBT-I.WT cells can rescue the melanoma-protection defect in Cd69–/– mice.
From: Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin
a, WT or Cd69–/– mice were transferred naive gBT-I.WT or gBT-I.Cd69–/– (1 × 105) cells, then inoculated epicutaneously with B16.gB cells and monitored for tumour development. b, Proportion of tumour-free non-developer WT (grey and black) or Cd69–/– (coloured) mice following tumour inoculation over time. Data pooled from n = 2 biologically independent experiments with n = 12 (gBT-I.WT→WT, gBT-I.Cd69–/–→WT), n = 14 (gBT-I.Cd69–/–→Cd69–/–) or n = 15 (gBT-I.WT→Cd69–/–) mice per group. *P = 0.0217, log-rank Mantel Cox test.
