Extended Data Fig. 7: Cell proliferation in multiple sclerosis.
From: Dynamics of oligodendrocyte generation in multiple sclerosis
a–d, Proliferating cells (Ki-67+, arrowheads, a–c) are sparse and proliferating OPCs are very rare (Ki-67+SOX10+, open arrowhead, d) in histological sections of shadow plaques (a–c) and adjacent NAWM (d) from patients with multiple sclerosis (n = 11). The box in a indicates the area shown in higher magnification (b) and the orthogonal view (c). Scale bars, 100 µm (a) and 10 µm (b–d). e, f, Quantification of Ki-67+ cells (e) and Ki-67+SOX10+ cells (f) in shadow plaque and adjacent NAWM in patients with multiple sclerosis (n = 11).
