Extended Data Fig. 2: Visualization of myelin in shadow plaques.
From: Dynamics of oligodendrocyte generation in multiple sclerosis
a, Overview of a carbon-dated multiple sclerosis tissue block reveals a shadow plaque and NAWM by eriochrome cyanine staining (n = 11). The shadow plaque is outlined by a dashed line. b–d, Higher magnification views of areas indicated by boxes in a show reduced myelin (proteolipid protein (PLP)) in all areas compared to NAWM. The images show patient case MS10. See also Supplementary Table 1. Scale bars, 2 mm (a) and 20 μm (b–d).
