Extended Data Fig. 2: Overview of mGlu5 cryo-EM studies.
From: Structural insights into the activation of metabotropic glutamate receptors
a, Two-dimensional negative-stain class averages of apo mGlu5 in LMNG shows several classes with split detergent micelles. b, c, Representative cryo-EM images of apo mGlu5 in nanodiscs (b) and active mGlu5 bound to l-quisqualate and Nb43 in GDN (c). d, e, Cryo-EM class averages of inactive (d) and active mGlu5 bound to l-quisqualate and Nb43 (e). f, Particle angular distribution of the final cryo-EM reconstructions of apo (left) and active (right) mGlu5.
