Extended Data Fig. 2: Glioma growth towards CSF spaces.
From: Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid
Representative brain MRI examples (T1 post-contrast) from patients with distinct patterns of tumour spread. Spread of enhancing disease to the pial, subependymal and subarachnoid spaces was used as an imaging surrogate to estimate tumour spread into the CSF, which is otherwise not visible by MRI. a, Enhancing leptomeningeal spread along bilateral cranial nerves VII and VIII (arrows). b, Enhancing pial spread to the surface of the pons (arrows). c, Nodular and curvilinear enhancing subependymal spread along both lateral ventricles (arrows).
