Extended Data Fig. 7: Detailed neuropathological characterization of lesions of multiple sclerosis.
From: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
Histology of the brains of patients with multiple sclerosis (labelled as patients MS-1 to MS-5) using haematoxylin and eosin (HE), luxol fast blue (LFB-PAS), 2′,3′-cyclic-nucleotide 3′-phosphodiesterase (CNPase) and myelin basic protein (MBP) for myelin, human leukocyte antigen DR isotype (HLA-DR) and CD68 for myeloid cells, CD3 for T cells, CD20 for B cells and Bielschowsky (Biel) for axons. Scale bar, 50 μm. Lesions are typical early active multiple-sclerosis lesions, according to the standard classification system36.
