Extended Data Fig. 7: Haematopoiesis in hypocretin-deficient mice. | Nature

Extended Data Fig. 7: Haematopoiesis in hypocretin-deficient mice.

From: Sleep modulates haematopoiesis and protects against atherosclerosis

Extended Data Fig. 7

ac, Quantification of the number of leukocytes in wild-type and Hcrt−/− mice at ZT3 in blood (a; n = 5 mice per group), spleen (b; for Ly-6Chigh monocytes and neutrophils, n = 7 wild-type mice and n = 8 Hcrt−/− mice; for B, CD8+ T, and CD4+ T cells, n = 5 wild-type mice and n = 6 Hcrt−/− mice) and bone marrow (c; for Ly-6Chigh monocytes and neutrophils, n = 7 wild-type mice and n = 8 Hcrt−/− mice; for B and T cells, n = 5 wild-type mice and n = 6 Hcrt−/− mice; for CMPs, GMPs and MDPs, n = 7 wild-type mice and n = 8 Hcrt−/− mice; for LSK populations, n = 5 wild-type mice and n = 6 Hcrt−/− mice). Data are mean ± s.e.m., **P < 0.01, ***P < 0.001, two-tailed Mann–Whitney U-tests.

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