Extended Data Fig. 5: Deconvolution and ΔF/F comparisons produce analogous findings in sister dendrites. | Nature

Extended Data Fig. 5: Deconvolution and ΔF/F comparisons produce analogous findings in sister dendrites.

From: Neuromodulatory control of localized dendritic spiking in critical period cortex

Extended Data Fig. 5

a, Top, time series showing ΔF/F and concurrent deconvolution for still and run epochs in a sister dendrite from a P28 mouse. Note the deconvolution is based on significant changes in slope. Spearman’s correlation coefficients (rs values) are shown. ΔF/F has been filtered for clarity. Bottom, as in the top panel for sister dendrites from a P56 mouse. Scale bar, ΔF/F = 1 and 1 s. Event probability = 1 AU. b, Median percentage change in ΔF/F from still to running, for all P28 and P56 branches (P28: n = 36 branches; P56: n = 96 branches). P = 0.6608, Mann–Whitney U-test. c, Correlation of ΔF/F between sister dendrites to movement at P28 or P56 (P28: n = 18 branch pairs; P56: n = 48 branch pairs). Still to run, ***P = 5.36 × 10−4 (P28), P = 0.043 (P56), Wilcoxon signed-rank test. N.S., not significant. Box plot parameters as in Fig. 1.

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