Extended Data Fig. 8: Measurement and modelling of optical aberrations.
From: Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
Threefold astigmatism (antisymmetrical; top) and fourfold astigmatism (symmetrical; bottom) measured in per-Fourier-pixel average phase-error plots (left) and represented by our parametric model (right) for CTE type I tau filaments from case 1. The plot shows image frequencies up to 2.9 Å. The outlier ring at 4.7 Å corresponds to the dominant frequency given by a double-repetition of the helix. This ring has been excluded from the parametric fit.
