Extended Data Fig. 2: Immunolabelling of tau filaments extracted from the brains of CTE cases 1–3.
From: Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
a, b, Immunoblots and immunolabelling of tau filaments extracted from the temporal cortices of CTE cases 1, 2 and 3. a, Immunoblots of sarkosyl-insoluble tau using antibodies BR136, anti-4R, BR135 and TauC4. b, Representative immuno-EM images of tau filaments labelled with antibodies BR136 and anti-4R. Unlike BR136 and anti-4R, antibodies BR135 and TauC4 did not label the filaments, which indicates that their epitopes lie within the ordered filament cores. Scale bar, 200 nm.
