Extended Data Fig. 3: Cryo-EM 2D and 3D classification.
From: Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules

a, Two-dimensional class averages spanning an entire helical crossover of type I and type II tau filaments from CTE cases 1–3. b, Cryo-EM structure of paired helical filaments from the temporal cortex of CTE case 1.