Extended Data Fig. 5: Cryo-EM map of type I tau filaments from CTE case 1.
From: Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
a–c, Close-up view of the cryo-EM map with the atomic model overlaid, showing densities for oxygens atoms of the peptide groups (a) and ordered solvent molecules (b). c, Side-chain conformations for the alternating positively and negatively charged solvent-exposed side chains of residues 336–343 in successive rungs.
