Extended Data Fig. 10: Frequently mutated residues converge in three-dimensional space.
From: The expanding landscape of ‘oncohistone’ mutations in human cancers
Examples of residues with α-carbons within 11.4 Å that are mutated ≥2.5-fold over the median counts per residue for each histone family, when a TMB ≤ 10 mutations per Mb threshold is applied. Residues of interest are mapped on the nucleosome structure (PDB code 1KX5).
