Extended Data Fig. 1: Sample characteristics.
From: The expanding landscape of ‘oncohistone’ mutations in human cancers
One sample per patient in which TMB ≤ 10 mutations per Mb is shown, except in c, in which all samples are represented regardless of the TMB. a, Tumour allele frequency distribution for 1,452 out of 1,921 tumours in which allele frequency is available based on publicly available data. b, Detailed tumour allele frequency distribution for the four most frequency mutated residues. Blue bars represent the median. c, TMB distribution. d, Tumour type distribution. For display purposes, the main cancer types are used in place of detailed cancer type. e, f, Oncoprint of the distribution of histone mutations between core families on a per patient level for all TMB values (e) and for TMB ≤ 10 mutations per Mb (f). For display purposes, H2A variants and H3.5 are not shown.
