Extended Data Fig. 8: Comparison of the V. cholerae and E. cloacae structures reveals two states of the gate in LptF.
From: Structural basis of unidirectional export of lipopolysaccharide to the cell surface
a, An overlay of the V. cholerae (LptG, teal; LptF, green; and LptC, magenta) and E. cloacae (LptG, grey; LptF, orange; and LptC, pink) structures shows two conformations of the loop between the third and fourth β-strands of the LptF periplasmic domain. b, Magnified view of this loop and an adjacent loop from LptC in the V. cholerae structure. LptF residues 179–183 and LptC residues 71–74 are depicted as sticks on top of the cartoon. c, Magnified view of the same region in E. cloacae. The 2Fo − Fc omit maps in b and c are contoured at 1.0σ and carved 2.5 Å from the protein.
