Extended Data Fig. 12: Glial cell structure in the hippocampus.
From: Restoration of brain circulation and cellular functions hours post-mortem
a, b, Confocal maximum intensity projections of immunohistochemical stains for astrocytes (GFAP; red) and microglia (IBA-1; green) with DAPI (blue) counterstain in the CA1 (a) and dentate gyrus (b) regions of the hippocampus show preservation of glial cell structure under BEx perfusion conditions. As compared to 1 h PMI controls, glial cells in BEx samples demonstrate a more reactive morphology with thickened cellular processes. Scale bar, 50 μm. Images are from a representative brain from each condition; experiments were repeated in n = 3 independent brains per group with similar results.
