Extended Data Table 5 Thermostability data

From: Structural basis of ligand recognition at the human MT1 melatonin receptor

  1. Melting temperature (Tm, mean ± s.d. for n = 3 independent experiments) for crystallized construct (MT1-CC) and several of its mutants purified in the absence (apo) and presence (100 µM) of ligand (mlt, melatonin; 2-PMT, 2-phenylmelatonin; rmt, ramelteon). ND, not determined. Melting curves are shown in Supplementary Fig. 4.