Extended Data Fig. 8: Whole-genome analyses of chromosomal arm copy number changes and mitochondrial genome representation.
From: Genome-wide cell-free DNA fragmentation in patients with cancer
a, Z-scores for each autosome arm are depicted for healthy individuals (n = 215) and patients with cancer (n = 208). The vertical axis depicts normal copy at zero with positive and negative values indicating arm gains and losses, respectively. Z-scores greater than 50 or less than −50 are thresholded at the indicated values. b, The fraction of reads mapping to the mitochondrial genome is depicted for healthy individuals (n = 215) and patients with cancer (n = 208). Box plots depict the minimum, 25th percentile, median, 75th percentile, and maximum values.
