Extended Data Fig. 10: Detection of cancer using DELFI and mutation-based cfDNA approaches.
From: Genome-wide cell-free DNA fragmentation in patients with cancer

DELFI (green) and targeted sequencing10 for mutation identification (blue) were performed independently in a cohort of 126 patients with breast, bile duct, colorectal, gastric, lung or ovarian cancer. The number of individuals detected by each approach and in combination are indicated for DELFI detection with a specificity of 98%, targeted sequencing specificity at >99%, and a combined specificity of 98%. ND, not detected.