Extended Data Fig. 8: Characteristics of off-target RNA SNVs in single cells.
From: Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
a, b, The ratio of shared SNVs between any two samples in the same group or with predicted off-target sites by Cas-OFFinder. The proportion in each cell is calculated by the number of overlapping SNVs between two samples divided by the sample in the row. c, Editing rate of BE3-induced non-synonymous mutations on oncogenes and tumour suppressor genes in single cells. d, Editing rate of ABE7.10-induced non-synonymous mutations on oncogenes and tumour suppressor genes in single cells. Gene names, amino acid mutations and single nucleotide conversions are indicated by blue, red and green, respectively.
