Extended Data Fig. 3: Mutation types and gene expression of off-target RNA SNVs.
From: Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
a, Distribution of mutation types in each repeat of all groups. The number in each cell indicates the percentage of a certain type of mutation among all mutations. b, Expression of genes containing overlapping off-target RNA SNVs and random simulated genes in all groups transfected with BE3 (n = 8 biologically independent samples) or ABE7.10 (n = 9 biologically independent samples). Two-sided unpaired t-test. Box-and-whisker plots: centre line indicates median, box represents first and third quantiles, and whiskers indicate maximum and minimum values.
