Extended Data Fig. 8: Quality control of microarray data.
From: Immune evasion before tumour invasion in early lung squamous carcinogenesis
a, Distribution of the relative abundance of each probe; that is, the ratio between the red and green colour intensity (Cy5/Cy3) for all probes across all patients (log2-transformed). b, Gene-expression distribution for each hybridization and amplification run (left). Using randomized principal component analysis, the samples were projected on the first two principal components and highlighted with different colours on the basis of their hybridization run (top right) and amplification run (bottom right). c, Classification of the samples is based on the expression of sex-chromosome genes, along with colour annotation for the sex of the patient.
